Synthetic Biology

In synthetic biology research, new biological systems are developed to enable the sustainable and environmentally friendly biomanufacturing of biochemicals and materials. Central to our efforts is the study and understanding of microbial metabolism, which enables the genetic reprogramming of cells for optimal energy and carbon utilization. This research involves the design and construction of microbial cell factories and consortia that produce valuable compounds from currently underutilized raw materials.

Our goal is to develop innovative strategies for utilizing challenging feedstocks, such as lignin, carbon dioxide, and plastic waste, thereby advancing circular economy principles and improving energy and resource efficiency. Through genetic engineering, microbes are tailored to produce customized compounds, including microbial oils, bacterial polymers, functional hydrocarbons, bioplastic monomers, and phytochemicals. We also model and develop molecular-level tools for genetic engineering, metabolic optimization, and the study of microbial physiology.

In addition to individual microbial strains, we construct, study, and model microbial consortia from the perspectives of bioprocessing and microbial ecology.