Ilari Mäki-Opas
Clinical Instructor, kliininen farmakologia
Faculty of Medicine and Health Technology | Internal and Respiratory medicine & Critical care, Skin & Allergy
Tampere University
ilari.maki-opas [at] tuni.fi (ilari[dot]maki-opas[at]tuni[dot]fi)
About me
My research interests include the role of TRPA1 ion channel in inflammatory diseases.
My publications at researchportal.tuni.fi
TUNICRIS Ilari Mäki-Opas
My research group
The Immunopharmacology Research Group
Latest publications
The Contact Allergen Methylisothiazolinone (MIT) is a Potent Activator of the TRPA1 Ion Channel
Mäki-Opas, I., Luostarinen, S., Hämäläinen, M., Muraki, K. & Moilanen, E., Jun 2025, In: Pharmacology Research and Perspectives. 13, 3, e70053.Research output: Contribution to journal › Article › Scientific › peer-review
TRPA1 as a potential factor and drug target in scleroderma: dermal fibrosis and alternative macrophage activation are attenuated in TRPA1-deficient mice in bleomycin-induced experimental model of scleroderma
Mäki-Opas, I., Hämäläinen, M., Moilanen, E. & Scotece, M., 2023, In: Arthritis Research and Therapy. 25, 1, 12.Research output: Contribution to journal › Article › Scientific › peer-review
TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene
Mäki-Opas, I., Hämäläinen, M., Moilanen, L. J., Sood, H., Leppänen, T., Kummola, L., Junttila, I. S., Lehtimäki, L. & Moilanen, E., 2023, In: Journal of Investigative Dermatology. 143, 6, p. 1104-1108.e4Research output: Contribution to journal › Letter › Scientific › peer-review
Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo
Mäki-Opas, I., Hämäläinen, M., Moilanen, L. J., Haavikko, R., Ahonen, T. J., Alakurtti, S., Moreira, V. M., Muraki, K., Yli-Kauhaluoma, J. & Moilanen, E., 2019, In: ACS Chemical Neuroscience. 10, 6, p. 2848-2857Research output: Contribution to journal › Article › Scientific › peer-review
Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner
Eräsalo, H., Hämäläinen, M., Leppänen, T., Mäki-Opas, I., Laavola, M., Haavikko, R., Yli-Kauhaluoma, J. & Moilanen, E., 2018, In: Journal of natural products. 81, 5, p. 1131-1142Research output: Contribution to journal › Article › Scientific › peer-review