

Nonappa Nonappa
About me
I lead a multidisciplinary team of researchers at the intersection of Chemistry, Materials Science, and Biomedical Sciences. My scientific journey has taken me across various disciplines, from organic and supramolecular chemistry to nanoparticle self-assembly, cryogenic electron microscopy, and the design of extracellular matrices for breast cancer models. This diverse background enables me to connect ideas and techniques in unconventional ways, often leading to discoveries that bridge chemistry, biology, and medicine. Our mission is to design, characterize, and engineer advanced materials, devices, and systems that enable precise control and manipulation at the molecular and cellular levels. One of my notable achievements is the development of a 3D hydrogel-based patient-derived breast cancer tissue culture model, which has been validated using over 1,000 patient samples. This innovation is paving the way for next-generation diagnostic tools and drug discovery platforms. We are also developing lab-on-a-chip technologies to model site-specific cancer metastasis, study disease progression, and enable real-time detection of biomarkers. Beyond biomedical applications, our team has pioneered biopolymer optical fibers for short-distance communications, including the first-ever demonstration of quantitative environmental sensing using such fibers. By effectively utilizing material stock and flow, creating a new value chain, and driving innovation in good health and well-being, our research activities support climate-neutral policies, the circular economy, the European Union's Green Deal, the UN´s Sustainable Development Goals, and Europe´s Beating Cancer Plan. For more information, see our Research Page and Publications.
Fields of expertise
- Breast cancer disease and diagnostic models
- Bio-based materials for optics and photonics
- Precision nanomaterials
- Advanced transmission electron microscopy
Research unit
Research career
Current position
- 03.08.2020-Present: Associate Professor (tenure track) in Nanochemistry, Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland.
Academic degrees and titles
- 19.10.2018: Abilitazione Scientifica Nazionale (ASN), CHIM/07-Fondamenti Chimici delle Tecnologie, MIUR, Italy.
- 26.05.2017: Title of Docent in Soft Matter Microscopy, School of Science, Department of Applied Physics, Aalto University, Finland
- 13.12.2008: Ph.D. in Organic Chemistry, Department of Organic Chemistry, Indian Institute of Science, Bangalore, India.
- 10.11.2020: Executive Master of Business Administration, Quantic School of Business and Technology, Washington D.C., USA.
Previous research experience
- 26.05.2017-31.07.2020: Research Fellow and Docent, Department of Applied Physics, School of Science, Aalto University, Finland
- 01.08.2012-25.05.2017: Postdoctoral Researcher, Department of Applied Physics, School of Science, Aalto University, Finland.
- 15.02.2009-31.07.2012: Postdoctoral Researcher, Department of Chemistry, University of Jyväskylä, Finland.
Selected publications
Visit our research group page for more details: https://research.tuni.fi/png/
Latest publications
Atomically precise noble metal nanoclusters for engineering self-assembled two-dimensional materials
Sethumadhavan, V. & Nonappa, 2025, In: DALTON TRANSACTIONS. 54, 31, p. 11770-11789Research output: Contribution to journal › Review Article › peer-review
Bimetallic Nanocluster-Based Light-Emitting Diodes With High External Quantum Efficiency and Saturated Red Emission
Rival, J. V., Chand, S., Jana, A., Nonappa, Biju, V., Pradeep, T., Rajamalli, P. & Shibu, E. S., 2025, (E-pub ahead of print) In: Advanced Materials.Research output: Contribution to journal › Article › Scientific › peer-review
Biopolymer Optical Fibers for High-Sensitivity Quantitative Humidity Monitoring
Patrakka, J., Hynninen, V., Huttunen, P. & Nonappa, 3 Sept 2025, In: ACS Applied Materials and Interfaces. 17, 35, p. 49816-49828 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Efficient Photocatalytic Hydrogen Production Using In-Situ Polymerized Gold Nanocluster Assemblies
Bera, D., Mahata, S., Biswas, M., Kumari, K., Rakshit, S., Nonappa, N., Ghosh, S. & Goswami, N., 2025, In: Small. 21, 1, 2406551.Research output: Contribution to journal › Article › Scientific › peer-review
Guided Heterostructure Growth of CoFe LDH on Ti3C2Tx MXene for Durably High Oxygen Evolution Activity
Sheng, J., Kang, J., Jiang, P., Meinander, K., Hong, X., Jiang, H., Nonappa, Ikkala, O., Komsa, H. P., Peng, B. & Lv, Z. P., 2025, In: Small. 21, 3, 2404927.Research output: Contribution to journal › Article › Scientific › peer-review
Morphology-Preserved Alloying in Anisotropic Gold Nanoparticles Using Atomically Precise Nanoclusters
Chakraborty, A., Manna, S., Mondal, B., Bodiuzzaman, M., Nagar, A., Chowdhury, S., Nayak, T., Nonappa, N. & Pradeep, T., 2 May 2025, (E-pub ahead of print) In: Small.Research output: Contribution to journal › Article › Scientific › peer-review
Nanocluster reaction-driven in situ transformation of colloidal nanoparticles to mesostructures
Bose, P., Srikrishnarka, P., Paatelainen, M., Nonappa, N., Kini, A. R., Som, A. & Pradeep, T., 2025, In: Nanoscale. 17, 2, p. 803-812Research output: Contribution to journal › Article › Scientific › peer-review
Nanofibrillar Cellulose Hydrogels with Anionic Surface Modifications for Modulating Macrophage Phenotype in 3D Culture
Heilala, M., Turpin, R., Pahimanolis, N., Nonappa, Ikkala, O., Klefström, J. & Munne, P. M., 2025, (E-pub ahead of print) In: ACS Applied Materials and Interfaces.Research output: Contribution to journal › Article › Scientific › peer-review
Optical Fiber Sensor with Dynamically Responsive Cladding for Real-Time Breath Pattern Monitoring
Pillalamarri, S., Patrakka, J., Sun, Z. & Nonappa, 30 Sept 2025, In: ACS Omega. 10, 38, p. 44528-44540 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Robust Self-Healing Metallo-Supergels of Folic Acid: Potential Sustainable Gelator for Oilfield Applications
Asgharian Marzabad, M., Chattopadhyay, S., Hietala, S., Nonappa, N., Marek, R. & Jurček, O., 5 May 2025, In: Chemistry - A European Journal. 31, 25, e202500748.Research output: Contribution to journal › Article › Scientific › peer-review