Pauli Losoi

Mostly I teach thermal sciences, or thermodynamics, fluid mechanics, and heat transfer, and supervise bachelor theses related to energy engineering. I also give lectures on industrial-scale bioreactors and teach how chemical reaction engineering can be applied to energy carrier processes (biorefining, catalytic transformations). The mathematics and application of modeling is of special interest both in research and teaching.

energy engineering, thermal sciences, bioengineering

• Analytical modeling of large-scale bioreactors using diffusion equations: perspectives on bioprocess design. Losoi P. (2025). Journal of Chemical Technology & Biotechnology. https://doi.org/10.1002/jctb.7838
• Modeling large-scale bioreactors with diffusion equations. Part I: Predicting axial dispersion coefficient and mixing times. Losoi P., Konttinen J., Santala V. (2024). Biotechnology and Bioengineering, 121, 1060–1075.. https://doi.org/10.1002/bit.28632 
• Modeling large-scale bioreactors with diffusion equations. Part II: Characterizing substrate, oxygen, temperature, carbon dioxide, and pH profiles. Losoi P., Konttinen J., Santala V. (2024). Biotechnology and Bioengineering, 121, 1102–1117. https://doi.org/10.1002/bit.28635 
• Substantial gradient mitigation in simulated large-scale bioreactors by optimally placed multiple feed points. Losoi P., Konttinen J., Santala V. (2022). Biotechnology and Bioengineering, 119, 3549-3566. https://doi.org/10.1002/bit.28232 
• Enhanced Population Control in a Synthetic Bacterial Consortium by Interconnected Carbon Cross-Feeding. Losoi P., Santala V., Santala S. (2019). ACS Synthetic Biology, 8(12), 2642-2650. https://doi.org/10.1021/acssynbio.9b00316