Fields of expertise
Microfluidics, (Micro)fabrication, Organ-on-chip applications, Biomimicking Cell Culture Technologies, Control of physiological conditions, Hypoxia, Mechanical stimulation (stretching)
Project links
Selected publications
Latest publications
A hypoxia-on-a-chip platform for modeling ischemic arrhythmogenesis and evaluating the effects of levosimendan and OR-1896 on ischemic human iPSC-derived cardiomyocytes
Gaballah, M., Walls, K., Zakzook, F., Kreutzer, J., Levijoki, J. & Aalto-Setälä, K., 2025, In: Frontiers in Bioengineering and Biotechnology. 13, 1671013.Research output: Contribution to journal › Article › Scientific › peer-review
Design, fabrication, and characterization of a user-friendly microfluidic device for studying liver zonation-on-chip (ZoC)
Mahdavi, R., Hashemi-Najafabadi, S., Ghiass, M. A., Valaskivi, S., Välimäki, H., Kreutzer, J., Hamngren Blomqvist, C., Romeo, S., Kallio, P. & Adiels, C. B., Mar 2025, In: BIOMEDICAL MICRODEVICES. 27, 1, 16 p., 8.Research output: Contribution to journal › Article › Scientific › peer-review
Barrier-free, open-top microfluidic chip for generating two distinct, interconnected 3D microvascular networks
Yrjänäinen, A., Mesiä, E., Lampela, E., Kreutzer, J., Vihinen, J., Tornberg, K., Vuorenpää, H., Miettinen, S., Kallio, P. & Mäki, A. J., 2 Oct 2024, In: Scientific Reports. 14, 1, 16 p., 22916.Research output: Contribution to journal › Article › Scientific › peer-review
Human tripartite cortical network model for temporal assessment of alpha-synuclein aggregation and propagation in Parkinson’s Disease
Kapucu, F. E., Tujula, I., Kulta, O., Sukki, L., Ryynänen, T., Gram, H., Vuolanto, V., Vinogradov, A., Kreutzer, J., Jensen, P. H., Kallio, P. & Narkilahti, S., 28 Jul 2024, In: NPJ Parkinson's disease. 10, 20 p., 138 .Research output: Contribution to journal › Article › Scientific › peer-review
Oxygen gradient generator to improve in vitro modeling of ischemic stroke
Santiago, J., Kreutzer, J., Bossink, E., Kallio, P. & le Feber, J., 28 Mar 2023, In: Frontiers in Neuroscience. 17, 13 p., 1110083.Research output: Contribution to journal › Article › Scientific › peer-review
Pneumatically actuated mechanobiological platform for cyclic cell stretching and compression studies
Kreutzer, J., Peussa, H., Ihalainen, T. & Kallio, P., 26 Jun 2023, p. 239-239.Research output: Other conference contribution › Poster › Scientific
Cardiac Ischemia On-a-Chip: Antiarrhythmic Effect of Levosimendan on Ischemic Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Gaballah, M., Penttinen, K., Kreutzer, J., Mäki, A. J., Kallio, P. & Aalto-Setälä, K., Mar 2022, In: Cells. 11, 6, 21 p., 1045.Research output: Contribution to journal › Article › Scientific › peer-review
Compartmentalized organ-on-a-chip structure for spatiotemporal control of oxygen microenvironments
Tornberg, K., Välimäki, H., Valaskivi, S., Mäki, A. J., Jokinen, M., Kreutzer, J. & Kallio, P., Oct 2022, In: BIOMEDICAL MICRODEVICES. 24, 4, 11 p., 34.Research output: Contribution to journal › Article › Scientific › peer-review
Electrophysiological Changes of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes during Acute Hypoxia and Reoxygenation
Häkli, M., Kreutzer, J., Mäki, A.-J., Välimäki, H., Cherian, R. M., Kallio, P., Aalto-Setälä, K. & Pekkanen-Mattila, M., Dec 2022, In: Stem Cells International. 2022, 15 p., 9438281.Research output: Contribution to journal › Article › Scientific › peer-review
M1-linked ubiquitination facilitates NF-κB activation and survival during sterile inflammation
Aalto, A., Martínez-Chacón, G., Kietz, C., Tsyganova, N., Kreutzer, J., Kallio, P., Broemer, M. & Meinander, A., 2022, In: FEBS Journal. 289, 7Research output: Contribution to journal › Article › Scientific › peer-review