BioInterfaces

We use molecular modelling tools and molecular dynamics simulations to study how the structural complexity of biological interfaces—such as the plasma membrane and the pulmonary surfactant monolayer—gives rise to their physiological functions. Currently, we are especially interested in understanding how membrane heterogeneity, asymmetry, and curvature regulate the localisation, structure, and function of membrane-embedded molecules such as transmembrane peptides and proteins. We also develop simulation models and methods, especially focusing on a physically sound atomistic model for the pulmonary surfactant.