Mandana Mombeinipour

My current research focuses on the "Modulation of phagocytosis and matrix remodeling by receptor nanoclustering". This work aims to control integrin clustering using novel adapter proteins to understand its influence on extracellular matrix remodeling and phagocytosis. 

·  Designing and validating molecular tools to control integrin receptor oligomerization.

·  Investigating the influence of controlled integrin oligomerization on extracellular matrix (ECM) remodeling

Extensive proficiency in Cell Culture, Tissue Engineering, and Co-culture Techniques. Skilled in a wide range of bioassays and methodologies.

• Design and validation of molecular tools: Produce a panel of recombinant protein tools to control the oligomeric state of target integrin receptors.
• Influence of the controlled integrin oligomerization on matrix remodeling

• Integrin nanoclustering
• Extracellular Matrix (ECM) remodeling

• Molecular Biology
• Biochemistry

• Diploma in advanced studies, Tissue Engineering, Regenerative Medicine and Stem Cells
  • University of Minho – Portugal (Sep. 2016 – June 2022)
• Master of Science: Molecular Biology
  • The University of Gothenburg – Sweden (Sep. 2014 – Jan. 2016)

• Romero, A. M., Maciaszczyk-Dziubinska, E., Mombeinipour, M., Lorentzon, E., Aspholm, E., Wysocki, R., & Tamás, M. J. (2022). Etp1 confers arsenite resistance by affecting ACR3 expression. FEMS Yeast Research, 22(1), foac018.
• Mombeinipour, M., Zare Mirakabadi, A., Mansuri, K., & Lotfi, M. (2013). In vivo and in vitro anti-angiogenesis effect of venom-derived peptides (ICD-85). Archives of Iranian Medicine, 16(2), 109-113. PMID: 23360634.