Julkaisut
Puhakka N, Das Gupta S, Leskinen S, Heiskanen M, Nättinen J, Aapola U, Uusitalo H, Pitkänen A. Proteomics of deep cervical lymph nodes after experimental traumatic brain injury. Neurotrauma reports Jun 2023:4(1): 359-366.
Vähätupa M, Nättinen J, Aapola U, Uusitalo-Järvinen H, Uusitalo H, Järvinen TAH. Proteomics analysis of R-Ras deficiency in oxygen induced retinopathy. Int J Mol Sci. 2023 Apr 26;24(9):7914.
Nättinen J, Aapola U, Nukareddy P, Uusitalo H. Clinical tear fluid proteomics – a novel tool in glaucoma research. Int J Mol Sci. 2022 Jul 23;23(15):8136.
Välimäki J, Nukareddy P, Uusitalo H, Aapola U. Intraluminal deposits: A rare cause of glaucoma drainage implant total obstruction. European Journal of Ophthalmology, 2022, May 16.
Nättinen J, Aapola U, Nukareddy P, Uusitalo H. Looking deeper into ocular surface health: an introduction to clinical tear proteomics analysis. Acta Ophthalmol 2022 Aug;100(5):486-498.
Nättinen J, Mäkinen P, Aapola U, Orsila L, Pietilä J, Uusitalo H. Early changes in tear film protein profiles after femtosecond LASIK surgery. Clin Proteomics. 2020 Oct 19;17:36.
Hongisto H, Dewing JM, Christensen DR, Scott J, Cree AJ, Nättinen J, Määttä J, Jylhä A, Aapola U, Uusitalo H, Kaarniranta K, Ratnayaka JA, Skottman H, Lotery AJ. In vitro stem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsby fundus dystrophy. J Pathol. 2020 Jul 15:e5506.
Vaajanen A, Nättinen J, Aapola U, Gielen F, Uusitalo H. The effect of successful trabeculectomy on the ocular surface and tear proteomics-a prospective cohort study with 1-year follow-up. Acta Ophthalmol. 2021 Mar;99(2):160-170. Epub 2020 Jul 9.
Nättinen J, Aapola U, Jylhä A, Vaajanen A, Uusitalo H. Comparison of capillary and Schirmer strip tear fluid sampling methods using SWATH-MS proteomics approach. Trans Vis Sci Tech 2020, 9(3): 16
Nättinen J, Jylhä A, Aapola U, Mäkinen P, Beuerman R, Pietilä J, Vaajanen A, Uusitalo H. Age-associated changes in human tear proteome. Clin Proteomics. 2019 Mar 30;16:11
Nättinen J, Jylhä A, Aapola U, Parkkari M, Mikhailova A, Beuerman R, Uusitalo H. Patient stratification in clinical glaucoma trials using the individual tear proteome. SciRep. 2018, 8:12038, doi:10.1038/s41598-018-30369-x.
Jylhä A, Nättinen J, Aapola U, Mikhailova A, Nykter M, Zhou L, Beuerman R, Uusitalo H. Comparison of iTRAQ and SWATH in a clinical study with multiple time points. ClinProteomics. 2018 Jul30;15:24. doi: 10.1186/s12014-018-9201-5. eCollection2018.
Vähätupa M, Nättinen J, Jylhä A, Aapola U, Kataja M, Kööbi P, Järvinen TAH, Uusitalo H, Uusitalo-Järvinen H. SWATH-MS Proteomic Analysis of Oxygen-Induced RetinopathyReveals Novel Potential Therapeutic Targets. Invest Ophthalmol Vis Sci. 2018 Jul2;59(8):3294-3306. doi: 10.1167/iovs.18-23831.
Latonen L, Afyounian E, Jylhä A, Nättinen J, Aapola U, Annala M, Kivinummi K, Tammela T, Beuerman R, Uusitalo H, Nykter M, Visakorpi T. Integrative analysis of the proteome in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression. Nat.Commun. 2018
Nättinen J, Jylhä A, Aapola U, Enríquez-de-Salamanca A, Pinto-Fraga J, López-Miguel A, González-García MJ, Stern ME, Calonge M, Zhou L, Nykter M, Uusitalo H, Beuerman R. Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears. Ocul. Surf. 2018;16(1):84-92
Mikhailova A, Jylhä A, Rieck J, Nättinen J, Ilmarinen T, Veréb Z, Aapola U, Beuerman R, Petrovski G, Uusitalo H, Skottman H. Comparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells. Sci Rep. 2015;5:14684
Hongisto H, Jylhä A, Nättinen J, Rieck J, Ilmarinen T,Veréb Z, Aapola U, Beuerman R, Petrovski G, Uusitalo H, Skottman H. Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium. Sci Rep. 2017;7:6016
Tong L, Zhou XY, Jylhä A, Aapola U, Liu DN, Koh SK, Tian D, Quah J, Uusitalo H, Beuerman RW, Zhou L. Quantitation of 47 Human Tear Proteins using High Resolution Multiple Reaction Monitoring (HR-MRM) Based-Mass Spectrometry. J. Prot 2015;115:36-48.
