Course Catalog 2013-2014
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Basic Pori International Postgraduate Open University

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Course Catalog 2013-2014

KEB-23406 Metabolic Engineering, 4 cr

Additional information

The course is suggested for 4-5 year Biotechnology or MSc Programme in Science and Bioengineering students.
Suitable for postgraduate studies
Will not be lectured year 2013-2014

Person responsible

Matti Karp, Ville Santala, Suvi Santala

Learning Outcomes

After passing the course the student can link changes in the genotype level to changes in the phenotype level. The student will have an understanding of in silico metabolic models in metabolic engineering and their interplay with in vivo methods. The student will be able to apply metabolic engineering to different problems in modern industrial microbe strain improvement. The course will include a practical case example during which the student will carry out a short laboratory project exemplifying the power of metabolic engineering.

Content

Content Core content Complementary knowledge Specialist knowledge
1. Methods in metabolic engineering: in silico     
2. Methods in metabolic engineering: in vivo     
3. Microbial metabolism   Metabolic pathways   
4. Mutations affecting metabolism   Engineering gene expression   
5. Case example: in silico and in vivo laboratory     

Instructions for students on how to achieve the learning outcomes

The grade will be determined on the basis of an exam. To pass the course with a grade 1 the student will have to score at least 50 % of the maximum points in the exam. A good understanding the core content will suffice to a grade 3. In order to earn a grade 4 or 5 the student will have to have a good or excellent understanding of complementary knowledge.

Assessment scale:

Numerical evaluation scale (1-5) will be used on the course

Partial passing:

Completion parts must belong to the same implementation

Study material

Type Name Author ISBN URL Edition, availability, ... Examination material Language
Lecture slides   Metabolic engineering   Suvi Santala         Yes    English  
Lecture slides   Metabolic engineering   Ville Santala         Yes    English  

Prerequisites

Course Mandatory/Advisable Description
KEB-23346 Molecular Biotechnology Mandatory   1
KEB-23336 Microbial Genetics Mandatory    

1 . Or KEB-23346 Geeniteknologian menetelmät or book exam from Glick and Pasternak: Molecular biotechnology, 4th edition

Prerequisite relations (Requires logging in to POP)



Correspondence of content

Course Corresponds course  Description 
KEB-23406 Metabolic Engineering, 4 cr BIO-2626 Metabolic Engineering, 4 cr  

Last modified09.08.2013